A Closer Look at Beta 2-Microglobulin (B2M)

Posted by sleepyguy in Prescription Sleep Medicine on February 17th, 2011

In all people, there is a physiological construct called the “blood/brain barrier.” Over the last several years there has been a lot of interest in using Beta 2-Microglobulin, or B2M, to gain a better understanding for whether or not there has been an improvement in the functioning of that blood/brain barrier. This has mainly come about as a result of the need to examine what scientists and health professionals refer to as brain toxicity and also the detoxification process within the brain.

There has been a growing interest in the issue of toxicity and detoxification due to an understanding of how B2M might be able to attach itself to certain metals and heavy metals such as mercury and free iron in the brain, allowing them to be neutralized and then shuttled out of the brain and the surrounding liquids cushioning the brain from possible injury.

One reason the possibility of using B2M as a method for assessing improvement in the blood/brain barrier and the ability to scavenge out such heavy metals is that Beta 2 Microglobulin seems to be so ubiquitous within certain areas of the blood/brain barrier and a person’s cerebrospinal fluid that bathes that same person’s brain and spinal column.

When B2M is noted in high levels in relation to other proteins within that blood/brain barrier and within the cerebral spinal fluid it is reasonable to assume that there could be oxidative (sometimes known as “rusting”) damage to the blood/brain barrier itself. It can also indicate that there might be a flaw in the proper function of that same barrier due to overexposure to some sort of heavy metal like mercury.

For those not up on what health professionals and scientists refer to as the “blood/brain barrier,” it is something that acts like a figurative sort of wall that prevents the passage of both acids and bases that could lead to immediate damage to the brain from even very slight pH changes to the liquid surrounding the brain. It is well known that even very slight changes to a body’s pH could have serious implications to health.

This is why being able to use something like B2M to assess possible issues with toxic levels of heavy metals that could affect the brain’s pH is so important. Scientists and health professionals know that it is extremely important that the brain be kept as free as possible from contamination by toxic agents such as mercury. Once found in numerous home thermostats and played with my children for years and years, mercury poisoning is insidious and potentially lethal.

Additionally, B2M assessment can lead to processes aimed preventing such metals from breaking out into certain organs of the body where these metals would also have to be metabolized before excretion from the urine. Naturally, such metals can do eventual damage to organs like the kidneys and deliver. In fact, there is no end to the havoc heavy metal poisoning can do to a human over a period of time.

People suffering from overexposure to mercury and other heavy metals that adversely impact the blood/brain barrier and then the brain itself may often be thought to be suffering from other medical conditions, which brain toxicity can mimic. This is unfortunate because the underlying issues are therefore never corrected in the brain can be adversely impacted permanently. In the worst cases such toxicity will lead to death.

Fortunately for all, a clear eyed understanding of the implications surrounding elevated levels of B2M is well understood by many medical professionals nowadays. In the past, as late as just a decade or so ago, this was not always the case and a person could go along continuing to be exposed to heavy metals or the accumulation of free irons, which eventually would lead to certain neurodegenerative disorders, especially the most well-known, Parkinson’s Disease.

Today, it is more important than ever that person’s demonstrating what might at first appear to be neurological deficit type disorders resembling Parkinson’s be fully evaluated for elevated levels of B2M in an effort to correctly diagnose the issue, itch might just be a heavy metal has wormed its way through the blood/brain barrier.

The use of chelation therapy first began during World War I in the treatment of poison gas victims. The most popular, Dimercaprol, was also known as the “British Anti-Lewisite” because of its effectiveness in binding “Lewisite,” the arsenic-laced poison gas so the kidneys could safely flush the poison from the body through the urine.

Following World War II several Navy personnel contracted lead poisoning from the paint used in the finishing of Navy ship hulls. This was the first use of the “EDTA” (EthyleneDiamine Tetra-acetic Acid) chelating agent to remove the toxic heavy metals from their bloodstream. This synthetic amino acid was preferred over Dimercaprol because it did not produce the same serious side effects.

To eliminate lead, mercury and iron from the body, chelation therapy acts as a detoxification agent. It attracts these heavy metals, inhibits their properties and make it possible for the body to eliminate them as a waste product.

Chelation therapy in the 1960’s rapidly became the US standard method of treatment for heavy metals in the blood from exposure to lead, arsenic and mercury because it enabled the body to eliminate these toxins.

Administered intravenously by a physician or taken in an oral formula, both provide detoxification to the body. However oral chelation formulas such as OC-Max produced by the Goldshield Elite Company deliver these elements in a convenient form that can be assimilated easily.

Many alternative medicine health practitioners believe that oral chelation therapy presents the most effective way to prevent and treat heart disease. The safety of oral chelation therapy in the treatment of hardening of the arteries was the subject of a five-year research study performed in 2002.

During this study, it was found that cholesterol levels in the body could be reduced through the use of the oral chelation agent EDTA, vitamin B12, royal jelly, vitamin C and several other nutrients. Taken in liquid or soft-gel capsule form, it provides the circulatory system with the additional support of chelating agents.

It is because oral chelation is convenient, inexpensive and easy to self-administer without visiting a doctor’s office or the use of needles that has made it the preferred method of this therapy.

The OC-Max formula which combines Serrazymes, Sodium HexaMetaPhosphate (”SHMP”) and EDTA, has been used successfully to eliminate mercury and iron from the bloodstream as well as in the reduction of calcified plaque from the arteries.

Using the oral chelation method of chelation therapy assists the body to eliminate dangerous plaque which can lead to heart disease, making it one of the most effective methods of natural detoxification available.

How to Control High Cholesterol with Nutritional Supplements

Many people are unaware that cholesterol is manufactured by your body as well as contained in many food products. The body needs a certain amount of cholesterol and the liver produces it to maintain the integrity of cell membranes. In fact only 10% of the cholesterol in your bloodstream is the result of food intake. Therefore, having high cholesterol may not be simply a result of your diet.

What Are Your Options?

If you are serious about controlling your high cholesterol levels and want to take a natural approach, a diet that includes leafy green vegetables as the best choice. Health research shows that adding a garlic, curcumin and turmeric can also be beneficial.

In order for the body to function at its optimal best it needs a consistent level of vigorous movement otherwise known as exercise. More than just a cosmetic benefits, exercise is vital to stimulate the bodily organs and help them perform their tasks in maintaining your health, such as regulating the LDL and HDL cholesterol levels in your blood. There are several different types of exercise movement systems to fit any body type, personality or temperament. Exercise has been proven to increase the level of HDL or “good” cholesterol while reducing LDL or “bad” cholesterol.

Garlic is an antique oxidant that he is a wonderful supplement that reduces high cholesterol, many people prefer to take garlic in a capsule rather than edit to their food. Garlic has been used for centuries as the natural remedy for a wide range of ailments including high blood pressure.

The well-known Indian spice Turmeric root or curcumin is a member of the ginger family that has been used successfully in several studies on controlling high cholesterol levels. Reducing the amount of oxidation of fatty acids is also another factor that helps to decrease the amount of LDL cholesterol in the blood.

In addition to garlic and turmeric, artichoke leaf extract works with your body can inhibit high cholesterol and triglycerides. It can also prevent the production of calcified plaque deposits on the walls of your arteries.

The antioxidant quality of green tea has been making headlines for its ability to reduce high cholesterol levels when taken as a beverage or in capsule form. In addition green tea contains a variety of vitamins, essential oils and polyphenols which provide many healthy benefits

The GoldShield Elite Company produces GarlicGuard and OC-Max, two nutritional supplements that can teach you in controlling your high cholesterol level. Even though many natural supplements have been proven effective and safe, you should always consult your physician before embarking on any new health regimen.


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